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Subchronic toxicity, immunoregulation and anti-breast tumor effect of Nordamnacantal, an anthraquinone extracted from the stems of Morinda citrifolia L.

Nadiah AbuNur Rizi ZamberiSwee Keong YeapNoraini NordinNurul Elyani MohamadMuhammad Firdaus RomliNurulfazlina Edayah RasolTamilselvan SubramaniNor Hadiani IsmailNoorjahan Banu Mohamed Alitheen
Published in: BMC complementary and alternative medicine (2018)
Nordamnacanthal managed to inhibit the growth and induce cell death in MDA-MB231 and MCF-7 cell lines in vitro and cease the tumor progression of 4T1 cells in vivo. Overall, nordamnacanthal holds interesting anti-cancer properties that can be further explored.
Keyphrases
  • cell death
  • breast cancer cells
  • cell cycle arrest
  • poor prognosis
  • oxidative stress
  • oxide nanoparticles