The heritability of amyloid burden in older adults: the Older Australian Twins Study.

Rebecca KonczAnbupalam ThalamuthuWei WenVibeke S CattsVincent DoreTeresa LeeKaren A MatherMelissa J SlavinEva A WegnerJiyang JiangJulian N TrollorDavid AmesVictor L VillemagneChristopher C RowePerminder Singh Sachdevnull null

Published in: Journal of neurology, neurosurgery, and psychiatry (2021)

Amyloid deposition, the hallmark early feature of Alzheimer's disease, is under moderate genetic influence, suggesting a major environmental contribution that may be amenable to intervention.

Keyphrases

physical activity
randomized controlled trial
machine learning
cognitive decline
deep learning
genome wide
risk factors
middle aged
gestational age
life cycle