NCI SEER-Linked Virtual Tissue Repository Pilot.

Pamela SanchezAlison L Van DykeValentina I PetkovYao YuanSarah BondsConnor ValenzuelaAlyssa W TuanRadim MoravecSean F AltekruseAatur D SinghiKate M SerdyYun WuRosemary D CressJennifer A DohertyLloyd MuellerBrenda Y HernandezCharles F LynchThomas C TuckerXiao-Cheng Wu Lynn M MatrisianLynne Penberthy

Published in: Journal of the National Cancer Institute. Monographs (2024)

The VTR Pilot demonstrated the feasibility of using SEER cancer registries as honest brokers to provide tissue and clinical data for secondary use in research. Studies using this program should oversample by 45% to 50% to obtain sufficient sample size and targeted population representation and involve subspecialty matter expert pathologists for tissue selection.

Keyphrases

study protocol
papillary thyroid
quality improvement
randomized controlled trial
machine learning
electronic health record
cancer therapy
big data
clinical practice
deep learning
artificial intelligence
neural network