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Network Pharmacology and Molecular Docking-Based Strategy to Investigate the Multitarget Mechanisms of Shenqi Yizhi Granule on Alzheimer's Disease.

Linshuang WangXiaoyu XuZikang WangQian ChenXiaodie WeiJingfan XueZhanjun ZhangMiao WangYanping LiJunying ZhangDongfeng Wei
Published in: Evidence-based complementary and alternative medicine : eCAM (2022)
The therapeutic mechanisms of SQYG on AD were associated with regulating lipid metabolism, metal ion metabolism, IL-17 signaling pathway, and GABA receptor signaling. Ginsenoside Rg1, tanshinone IIA, baicalin, astragaloside IV, and folic acid may play an important role in AD treatment.
Keyphrases
  • molecular docking
  • signaling pathway
  • molecular dynamics simulations
  • pi k akt
  • epithelial mesenchymal transition
  • cognitive decline
  • fatty acid
  • oxidative stress