Micelle enabled C(sp2)-C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis.
Ning YeBin WuKangming ZhaoXiaobin GeYu ZhengXiaodong ShenLei ShiMargery Cortes-ClergetMorgan Louis RegnierMichael ParmentierFabrice GallouPublished in: Chemical communications (Cambridge, England) (2021)
A robust and sustainable C(sp2)-C(sp3) cross-electrophile coupling was developed via nickel/copper synergistic catalysis under micellar conditions. This protocol provided a general method to access alkylated arenes with good to excellent yields on a very large scale.