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Fatty acid desaturase genetic variations and dietary omega-3 fatty acid intake associate with arterial stiffness.

Magnus BäckConstance XhaardRaphael RougetQuentin ThuillierOscar PlundeSusanna C LarssonNicolas GirerdJoão Pedro FerreiraJean-Marc BoivinErwan BozecLudovic MerckléFaiez ZannadAxelle HogeMichèle GuillaumeClaire Dandine-RoullandEdith Le FlochDelphine Bacq-DaianJean François DeleuzeLaurie Van den BergheJulie-Anne NazareMartine LavilleChristiane BranlantIsabelle Behm-AnsmantSandra WagnerPatrick Rossignol
Published in: European heart journal open (2022)
Taken together, these findings point to FADS1 genotype-dependent associations of omega-3 PUFA intake on subclinical cardiovascular disease. These findings may have implications for identifying responders and non-responders to omega-3 PUFA supplementation and open up for personalized dietary counselling in cardiovascular prevention.
Keyphrases
  • fatty acid
  • cardiovascular disease
  • blood pressure
  • weight gain
  • genome wide
  • gene expression
  • body mass index
  • copy number
  • weight loss