IL-10-modulated dendritic cells from birch pollen- and hazelnut-allergic patients facilitate Treg-mediated allergen-specific and cross-reactive tolerance.
Patricia Vanessa HeinlEdith GraulichBenno WeigmannAndrea WangorschRobert OseIris BellinghausenRahul KhatriVerena K RakerStephan ScheurerStefan ViethsJoachim SalogaKerstin SteinbrinkPublished in: Allergy (2024)
Human IL-10 DC-induced iTreg facilitate allergen-specific and cross-reactive tolerance. Therefore, they are potential candidates for regulatory cell therapy in allergic and autoimmune diseases.
Keyphrases
- dendritic cells
- cell therapy
- allergic rhinitis
- end stage renal disease
- endothelial cells
- ejection fraction
- newly diagnosed
- stem cells
- high glucose
- immune response
- prognostic factors
- diabetic rats
- transcription factor
- peritoneal dialysis
- patient reported outcomes
- induced pluripotent stem cells
- oxidative stress
- drug induced
- bone marrow
- patient reported
- climate change
- pluripotent stem cells