Efficacy and safety of ramucirumab-containing chemotherapy in patients with pretreated metastatic gastric neuroendocrine carcinoma.

Saori MishimaAkihito KawazoeHiroshi MatsumotoYasutoshi KubokiHideaki BandoTakashi KojimaToshihiko DoiAtsushi OhtsuTakayuki YoshinoElizabeth M NonteSudhakar ChintharlapalliAejaz NasirTakeshi KuwataKohei Shitara

Published in: ESMO open (2018)

RAM-CTx showed a promising activity without severe or unexpected safety profile in pts with G-NEC. This may in part be explained by higher vascular VEGFR2 expression in G-NEC tissues.

Keyphrases

poor prognosis
squamous cell carcinoma
small cell lung cancer
gene expression
locally advanced
early onset
vascular endothelial growth factor
klebsiella pneumoniae
binding protein
escherichia coli