Subclinical impairment of dynamic left ventricular systolic and diastolic function in patients with obstructive sleep apnea and preserved left ventricular ejection fraction.
Antonello D'AndreaAngelo CanoraSimona SperlonganoDomenico GalatiSerena ZanottaGiorgio Emanuele PolistinaCarmine NicolettaGiacomo GhinassiMaurizio GalderisiAlessandro Sanduzzi ZamparelliPatrizio LancellottiMarialuisa BocchinoPublished in: BMC pulmonary medicine (2020)
Evaluation of diastolic function and myocardial deformation during exercise is feasible through stress echocardiography. OSA patients with preserved LVEF show subclinical LV systolic dysfunction, impaired LV systolic and diastolic reserve, reduced exercise tolerance, and increased peripheral levels of OB. Therapy aimed at increasing LV diastolic function reserve might improve the quality of life and exercise tolerability in OSA patients.
Keyphrases
- aortic valve
- left ventricular
- ejection fraction
- aortic stenosis
- obstructive sleep apnea
- high intensity
- hypertrophic cardiomyopathy
- cardiac resynchronization therapy
- acute myocardial infarction
- positive airway pressure
- heart failure
- mitral valve
- left atrial
- physical activity
- end stage renal disease
- resistance training
- blood pressure
- newly diagnosed
- chronic kidney disease
- stem cells
- oxidative stress
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- computed tomography
- pulmonary hypertension
- body composition
- clinical trial
- study protocol
- acute coronary syndrome
- stress induced
- heat stress