Evidence for interaction between genetic liability and childhood trauma in the development of psychotic symptoms.
Florentina M E PinckaersIris L M RoteeC Vicky NwosuPauline KrolinskiAntonius P W SmeetsSinan GülöksüzLea de JongThomas S J VaessenThomas DamenAniek UittenboogaardAnnika T SchäferClaudia Menne-LothmannJeroen DecosterRuud van WinkelDina CollipPhilippe DelespaulMarc De HertCatherine DeromEvert ThieryNele JacobsMarieke WichersBart P F RuttenJim van OsMarjan DrukkerPublished in: Social psychiatry and psychiatric epidemiology (2019)
The results suggest that the impact of CT on subthreshold expression of psychosis, particularly in the negative subdomain, may be larger in the co-presence of significant genetic liability for psychopathology.