Polymorphisms and gene expression of metalloproteinases and their inhibitors associated with cerebral ischemic stroke in young patients with sickle cell anemia.
Kleyton Palmeira do ÓAna Karla da Silva FreireDébora Nascimento da NóbregaRoberta Dos Santos SouzaIsabela Cristina Cordeiro FariasTaciana Furtado de Mendonça BelmontAndreia Soares da SilvaGabriela S ArcanjoAderson da Silva AraujoAna Cláudia Mendonça Dos AnjosAntônio Roberto Lucena de AraujoMarcos André Cavalcanti BezerraPatricia Muniz Mendes Freire de MouraMaria do Socorro Mendonça CavalcantiLuydson Richardson da Silva VasconcelosPublished in: Molecular biology reports (2023)
The findings of this study, the SNPs, and expression provide initial support for understanding the role of MMPs-TIMPs in the pathophysiology of SCA in young patients.