RNA interference mediated suppression of TRPV6 inhibits the progression of prostate cancer in vitro by modulating cathepsin B and MMP9 expression.

Duk Yoon Kim Soon Hee Kim Eun Kyoung Yang

Published in: Investigative and clinical urology (2021)

The results indicate that TRPV6 may promote prostate cancer progression in association with MMP9 and cathepsin B, thereby validating further research into TRPV6 as a useful therapeutic target for local invasion or metastasis of advanced prostate cancer.

Keyphrases

prostate cancer
radical prostatectomy
cell migration
neuropathic pain
poor prognosis
signaling pathway
binding protein