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The Preventive Effect of the Phenotype of Tumour-Associated Macrophages, Regulated by CD39, on Colon Cancer in Mice.

Hyun-Jun ParkEun-Hye SeoLiyun PiaoSang-Tae ParkMin-Ki LeeSeong-Eun KohSeung-Hyun LeeSeong-Hyop Kim
Published in: International journal of molecular sciences (2021)
The inhibition of CD39 with POM-1 prevented the growth of colon cancer in mice, and it was associated with the increased expression of M1-tumour phenotypes from TAMs in the cancer tissue.
Keyphrases
  • high fat diet induced
  • poor prognosis
  • papillary thyroid
  • squamous cell
  • squamous cell carcinoma
  • insulin resistance
  • metabolic syndrome
  • young adults
  • adipose tissue
  • long non coding rna
  • skeletal muscle
  • childhood cancer