The Preventive Effect of the Phenotype of Tumour-Associated Macrophages, Regulated by CD39, on Colon Cancer in Mice.
Hyun-Jun ParkEun-Hye SeoLiyun PiaoSang-Tae ParkMin-Ki LeeSeong-Eun KohSeung-Hyun LeeSeong-Hyop KimPublished in: International journal of molecular sciences (2021)
The inhibition of CD39 with POM-1 prevented the growth of colon cancer in mice, and it was associated with the increased expression of M1-tumour phenotypes from TAMs in the cancer tissue.