Comparison of two durations of triple-drug therapy in patients with uncomplicated brucellosis: A randomized controlled trial.
Masoomeh SofianAli-Akbar VelayatiArezoo AghakhaniWilli McFarlandAli-Asghar FaraziMohammad BanifazlAli EslamifarAmitis RamezaniPublished in: Scandinavian journal of infectious diseases (2014)
Our trial found no significant difference between 6-week and 8-week regimens of doxycycline and rifampicin plus streptomycin for the first 7 days. Further comparative studies with a large sample size should be implemented to achieve a consistent therapeutic regimen for uncomplicated brucellosis, to help identify those who may benefit from longer treatment, and to minimize adverse effects and unnecessary continuation of treatment.