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Comparison of two durations of triple-drug therapy in patients with uncomplicated brucellosis: A randomized controlled trial.

Masoomeh SofianAli-Akbar VelayatiArezoo AghakhaniWilli McFarlandAli-Asghar FaraziMohammad BanifazlAli EslamifarAmitis Ramezani
Published in: Scandinavian journal of infectious diseases (2014)
Our trial found no significant difference between 6-week and 8-week regimens of doxycycline and rifampicin plus streptomycin for the first 7 days. Further comparative studies with a large sample size should be implemented to achieve a consistent therapeutic regimen for uncomplicated brucellosis, to help identify those who may benefit from longer treatment, and to minimize adverse effects and unnecessary continuation of treatment.
Keyphrases
  • clinical trial
  • randomized controlled trial
  • stem cells
  • mycobacterium tuberculosis
  • emergency department
  • bone marrow
  • placebo controlled
  • cell therapy
  • open label
  • adverse drug
  • case control