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Low-density-lipoprotein cholesterol and mortality outcomes among healthy older adults: A post-hoc analysis of ASPREE trial.

Zhen ZhouAndrew M TonkinAndrea J CurtisAnne MurrayChao ZhuChristopher M ReidJeff D WilliamsonJoanne RyanJohn J McNeillLawrence J BeilinMichael E ErnstNigel StocksPaul A LacazeRaj C ShahRobyn L WoodsRory WolfeSeana GallSophia ZoungasSuzanne G OrchardMark R Nelson
Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)
There were U-shaped relationships between LDL-c and all-cause mortality, cancer mortality, and non-cancer/non-CVD mortality in healthy older adults. Higher LDL-c levels were associated with an increased risk of CVD mortality. Future studies are warranted to confirm our results.
Keyphrases
  • cardiovascular events
  • papillary thyroid
  • risk factors
  • physical activity
  • clinical trial
  • squamous cell carcinoma
  • type diabetes
  • randomized controlled trial
  • coronary artery disease
  • case control