Low-density-lipoprotein cholesterol and mortality outcomes among healthy older adults: A post-hoc analysis of ASPREE trial.
Zhen ZhouAndrew M TonkinAndrea J CurtisAnne MurrayChao ZhuChristopher M ReidJeff D WilliamsonJoanne RyanJohn J McNeillLawrence J BeilinMichael E ErnstNigel StocksPaul A LacazeRaj C ShahRobyn L WoodsRory WolfeSeana GallSophia ZoungasSuzanne G OrchardMark R NelsonPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)
There were U-shaped relationships between LDL-c and all-cause mortality, cancer mortality, and non-cancer/non-CVD mortality in healthy older adults. Higher LDL-c levels were associated with an increased risk of CVD mortality. Future studies are warranted to confirm our results.