The Arp2/3 inhibitory protein Arpin inhibits homology-directed DNA repair.

Gleb SimanovNathalie RocquesStéphane RomeroLeanne de KoningSophie VacherThierry DuboisIvan BiècheAlexis M Gautreau

Published in: Biology of the cell (2024)

Loss of Arpin expression coordinates enhanced cell migration with up-regulated DNA repair, which is required when DNA damage is induced by active cell migration.

Keyphrases

cell migration
dna repair
dna damage
poor prognosis
dna damage response
binding protein
oxidative stress
transcription factor
long non coding rna