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Myeloid Cell Glucocorticoid, Not Mineralocorticoid Receptor Signaling, Contributes to Salt-Sensitive Hypertension in Humans via Cortisol.

Claude F AlbrittonMert DemirciKit NeikirkLale A ErtugluJeanne A IshimweAshley L MutchlerQuanhu ShengCheryl L LafferCelestine N WanjallaTaseer AhmedAlexandria Porcia HaynesMohammad SaleemHeather K BeasleyAndrea G MarshallZer VueAlp T IkizlerThomas R KleymanValentina KonAntentor O HintonAnnet Kirabo
Published in: bioRxiv : the preprint server for biology (2024)
expression. A cortisol-driven mechanism could provide a practical approach for targeted treatments for salt-sensitive hypertension. Moreover, it could pave the way for a diagnostic approach.
Keyphrases
  • blood pressure
  • poor prognosis
  • single cell
  • dendritic cells
  • cell therapy
  • acute myeloid leukemia
  • cancer therapy
  • immune response
  • drug delivery