Myeloid Cell Glucocorticoid, Not Mineralocorticoid Receptor Signaling, Contributes to Salt-Sensitive Hypertension in Humans via Cortisol.

Claude F AlbrittonMert DemirciKit NeikirkLale A ErtugluJeanne A IshimweAshley L MutchlerQuanhu ShengCheryl L LafferCelestine N WanjallaTaseer AhmedAlexandria Porcia HaynesMohammad SaleemHeather K BeasleyAndrea G MarshallZer VueAlp T IkizlerThomas R KleymanValentina KonAntentor O HintonAnnet Kirabo

Published in: bioRxiv : the preprint server for biology (2024)

expression. A cortisol-driven mechanism could provide a practical approach for targeted treatments for salt-sensitive hypertension. Moreover, it could pave the way for a diagnostic approach.

Keyphrases

blood pressure
poor prognosis
single cell
dendritic cells
cell therapy
acute myeloid leukemia
cancer therapy
immune response
drug delivery