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Transcriptome analysis of non human primate-induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer culture vs. 3D engineered heart tissue.

Huaxiao YangNing-Yi ShaoAlexandra HolmströmXin ZhaoTony ChourHaodong ChenIlanit ItzhakiHaodi WuMohamed AmeenNathan J CunninghamChengyi TuMing-Tao ZhaoAlice F TarantalOscar J AbilezJoseph C Wu
Published in: Cardiovascular research (2022)
By exposing NHP iPSC-CMs to different culture conditions, transcriptome profiling improves our understanding of the mechanism of ischaemic injury.
Keyphrases
  • high glucose
  • endothelial cells
  • induced pluripotent stem cells
  • single cell
  • rna seq
  • heart failure
  • diabetic rats
  • gene expression
  • pluripotent stem cells
  • atrial fibrillation
  • drug induced
  • oxidative stress