CD36 expression on oral squamous cell carcinoma cells correlates with enhanced proliferation and migratory activity.

Kotaro SakuraiKei TomiharaManabu YamazakiWataru HeshikiRohan MoniruzzamanKatsuhisa SekidoHidetake TachinamiAtsushi IkedaShuichi ImaueKumiko FujiwaraMakoto Noguchi

Published in: Oral diseases (2020)

Our results strongly suggest that CD36 has an important role in facilitating the proliferation and migration activity of OSCC cells, indicating its usefulness in the diagnosis of high-grade tumour and targeted therapy of oral cancer.

Keyphrases

induced apoptosis
high grade
cell cycle arrest
signaling pathway
poor prognosis
endoplasmic reticulum stress
cell proliferation