Liraglutide restores late cardioprotective effects of remote preconditioning in diabetic rats via activation of hydrogen sulfide and nuclear factor erythroid 2-related factor 2 signaling pathway.
Lingling WangYinyan TangHuimin HeWeirong WeiPublished in: Acta cirurgica brasileira (2021)
Liraglutide restores the lost cardioprotective effects of remote preconditioning in diabetes by increasing the expression of Nrf2, H2S and HIF-1α.
Keyphrases
- diabetic rats
- nuclear factor
- oxidative stress
- ischemia reperfusion injury
- toll like receptor
- signaling pathway
- induced apoptosis
- poor prognosis
- type diabetes
- cerebral ischemia
- cardiovascular disease
- pi k akt
- glycemic control
- epithelial mesenchymal transition
- endothelial cells
- immune response
- long non coding rna
- binding protein
- adipose tissue
- metabolic syndrome
- weight loss