YAP1 acts as a negative regulator of pro-tumor TAZ expression in esophageal squamous cell carcinoma.
Yi-Zih KuoYa-Rong KangWei-Lun ChangLydia Chin-Ling SimTzu-Chin HsiehChu-Han ChangYi-Ching WangChing-Jung TsaiLi-Chun HuangSen-Tien TsaiLi-Wha WuPublished in: Cellular oncology (Dordrecht) (2022)
From our data we conclude that YAP1 functions as a suppressor and negatively regulates pro-tumor TAZ expression via transcriptional and translational control in esophageal cancer.