Hepatorenal dysfunction identifies high-risk patients with acute heart failure: insights from the RELAX-AHF trial.

Jan BiegusBiniyam DemisseiDouwe PostmusGad CotterBeth A DavisonG Michael FelkerGerasimos FilippatosClaudio GimpelewiczBarry GreenbergMarco MetraThomas SeverinJohn R TeerlinkAdriaan A VoorsPiotr Ponikowski

Published in: ESC heart failure (2019)

In patients with AHF, hepatorenal dysfunction is prevalent and related to poor outcome. The MELD-XI score is a useful prognosticator in AHF.

Keyphrases

acute heart failure
heart failure
oxidative stress
study protocol
clinical trial
genome wide
phase iii
phase ii
randomized controlled trial
gene expression
dna methylation
double blind
placebo controlled