Transcriptomic Profiling of Primary Prostate Cancers and Nonlocalized Disease on Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography: A Multicenter Retrospective Study.
John NikitasKritika SubramanianNimrod Barashi GozalAndres Ricaurte-FajardoEric V LiJames A ProudfootElai DavicioniAriel E MarciscanoJoseph R OsborneChristopher E BarbieriWesley R ArmstrongClayton P SmithLuca F ValleMichael L SteinbergPaul C BoutrosNicholas G NickolsMatthew B RettigRobert E ReiterAdam B WeinerJeremie CalaisJohannes CzerninAshley Evan RossEric H KimHimanshu NagarAmar U KishanPublished in: JCO precision oncology (2024)
Higher Decipher scores were associated with nonlocalized disease identified on PSMA PET/CT both pretreatment and post-RP. There were several transcriptomic differences between localized and nonlocalized diseases in both settings.