Efficacy of commonly prescribed analgesics in the management of osteoarthritis: a systematic review and meta-analysis.

Mohan Stewart Jolanda Cibere Eric C Sayre Jacek A Kopec

Published in: Rheumatology international (2018)

The effects of 5 major drug categories in the treatment of OA pain were reviewed with data extracted from 29 studies published from 2006 to 2016. Acetaminophen was found to have an RC value close to that of oral NSAIDs. The effects of oral NSAIDs, COX-2 inhibitors, and opioids in controlling pain were similar to what has been demonstrated in previous literature. Topical NSAIDs were found to have a greater RC than oral NSAIDs.

Keyphrases

chronic pain
pain management
anti inflammatory drugs
systematic review
neuropathic pain
knee osteoarthritis
randomized controlled trial
electronic health record
postoperative pain
big data
machine learning
replacement therapy
data analysis