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Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis.

Rony Chanoch-MyersAdi WiderMario L SuvaMichael Mints
Published in: Genome medicine (2022)
Diverse MES states occur in glioblastoma. These states share a subset of core genes but differ primarily in their association with hypoxia vs. astrocytic expression programs, and with immune suppression vs. activation, respectively.
Keyphrases
  • poor prognosis
  • public health
  • endothelial cells
  • gene expression
  • binding protein
  • dna methylation