Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis.
Rony Chanoch-MyersAdi WiderMario L SuvaMichael MintsPublished in: Genome medicine (2022)
Diverse MES states occur in glioblastoma. These states share a subset of core genes but differ primarily in their association with hypoxia vs. astrocytic expression programs, and with immune suppression vs. activation, respectively.