Longitudinal changes in ventricular size and function are associated with death and transplantation late after the Fontan operation.
Sunil J GhelaniMinmin LuLynn A SleeperAshwin PrakashDaniel A CastellanosNicole St ClairAndrew J PowellRahul H RathodPublished in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2022)
Ventricles in the Fontan circulation exhibit a steady decline in performance with an increase in EDVI, ESVI, and ESWS, and decrease in EF, mass index, and mass-to-volume ratio. Those with death or need for heart transplantation have a faster increase in EDVI. Patients with rapid increase in EDVI (> 5 ml/BSA<sup>1.3</sup>/year) may be at a higher risk of adverse outcomes and may benefit from closer surveillance. RV dominance is associated with worse clinical outcomes and remodeling compared to LV dominance.