Changes in the Expression of Insulin Pathway, Neutrophil Elastase and Alpha 1 Antitrypsin Genes from Leukocytes of Young Individuals with Insulin Resistance.

Walter David Cruz-PinedaOlga Lilia Garibay-CerdenaresHugo Alberto Rodríguez-RuízInés Matia-GarcíaLinda Anahí Marino-OrtegaMónica Espinoza-RojoZyanya Reyes-CastilloNatividad Castro-AlarcónEduardo Castañeda-SaucedoBerenice Illades-AguiarIsela Parra-Rojas

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2022)

These results suggest that hyperinsulinemia and obesity are associated with changes in the expression of genes in leukocytes involved in the insulin pathway that are related to NE and A1AT.

Keyphrases

type diabetes
insulin resistance
poor prognosis
metabolic syndrome
glycemic control
genome wide
peripheral blood
adipose tissue
high fat diet induced
binding protein
skeletal muscle
high fat diet
weight loss
long non coding rna
body mass index