Dupilumab significantly improves skin barrier function in patients with moderate-to-severe atopic dermatitis.
Evgeny V BerdyshevElena GolevaRobert BissonnetteIrina BronovaAnna Sofia BronoffBrittany N RichersShannon GarciaMarco Ramirez-GamaPatricia TaylorAmy PraestgaardInoncent AgueusopPauline JurvilliersMark BoguniewiczNoah A LevitAna Beatris RossiAnnie ZhangDonald Y M LeungPublished in: Allergy (2022)
Inhibition of IL-4/IL-13 signaling by dupilumab allows restoration of skin lipid composition and barrier function in patients with moderate-to-severe AD.