An efficient method for highly selective alkenyl C-P bond cleavage, enabled by organic dyes and visible-light irradiation, was developed. This novel protocol involves a highly regioselective radical pathway initiated by singlet oxygen, affording diverse alkynyl phosphinates with good-to-excellent yields. Mechanistic studies and density functional theory calculations suggested an intramolecular process involving phosphorus migration, instead of phosphorus radical formation, at the early stage of the reaction.
Keyphrases
- visible light
- density functional theory
- early stage
- molecular dynamics
- dna binding
- sewage sludge
- randomized controlled trial
- energy transfer
- electron transfer
- transition metal
- sentinel lymph node
- case control
- transcription factor
- squamous cell carcinoma
- radiation therapy
- quantum dots
- molecular dynamics simulations
- anaerobic digestion
- risk assessment