Long-term results of ESS in CRSwNP can be branched in PROMs and other objective measurements. Despite the heterogeneity of reported outcomes make it difficult to perform comparisons and meta-analysis, ESS improves PROMs, including symptoms, QOL and olfaction. Objectives outcomes such as NPS, LMS, type of surgery, or recurrence and revision surgery don't have a clear role in long-term results. Clustering patients suggest asthma, N-ERD, allergy, eosinophil count and IL-5 could have a role in predicting recurrence and severe disease. Long-term studies of CRSwNP treated with ESS are scarce. There is a significant need to standardize the report of results. The use of tools as SNOT-22, NPS, validated smell tests, defined criteria for disease recurrence and control and ESS extension in a unified systematic way could allow better comparisons between treatments in the new era of biologics.
Keyphrases
- patient reported outcomes
- minimally invasive
- coronary artery bypass
- systematic review
- end stage renal disease
- newly diagnosed
- free survival
- single cell
- surgical site infection
- chronic obstructive pulmonary disease
- chronic kidney disease
- total knee arthroplasty
- prognostic factors
- randomized controlled trial
- type diabetes
- depressive symptoms
- early onset
- insulin resistance
- ultrasound guided
- rna seq
- physical activity
- adipose tissue
- coronary artery disease