Ten-day high-dose proton pump inhibitor triple therapy versus sequential therapy for Helicobacter pylori eradication.
Chonticha AuesomwangMonthira ManeerattanapornWilliam D CheyPattarachai KiratisinSomchai LeelakusolwongTawesak TanwandeePublished in: Journal of gastroenterology and hepatology (2018)
Sequential therapy achieved better H. pylori eradication than HD-PPI-TT in patients with FD. However, the eradication rate for ST fell from 94.4% in per protocol to 85% in intention-to-treat analysis. Adverse effects might result in poorer compliance and compromise actual ST efficacy (ClinicalTrials.gov: NCT01888237).