Login / Signup

Expression of the Chemokine Receptor CCR7 in the Normal Adrenal Gland and Adrenal Tumors and Its Correlation with Clinical Outcome in Adrenocortical Carcinoma.

Carmina Teresa FussKatharina OtherBritta HeinzeLaura-Sophie LandwehrArmin WiegeringCharis KalogirouStefanie HahnerFassnacht Martin
Published in: Cancers (2021)
We show that CCR7 is expressed on mRNA and protein level across normal adrenals, benign adrenocortical tumors, as well as ACCs. Given that CCR7 did not influence survival in ACC, it is probably not involved in tumor progression, but it could play a role in adrenocortical homeostasis.
Keyphrases
  • poor prognosis
  • binding protein
  • dendritic cells
  • regulatory t cells
  • long non coding rna