Cancer Stem Cells and Cell Cycle Genes as Independent Predictors of Relapse in Non-small Cell Lung Cancer: Secondary Analysis of a Prospective Study.

Valentina MascialeFederico BanchelliGiulia GrisendiRoberto D'AmicoAntonino MaioranaAlessandro StefaniUliano MorandiFranco StellaMassimo DominiciBeatrice Aramini

Published in: Stem cells translational medicine (2022)

CSCs frequency and RG expression are independent predictors of relapse in lung cancer. Considering these results, CSCs and RG may be considered for both target therapy and prognosis.

Keyphrases

cancer stem cells
cell cycle
cell proliferation
poor prognosis
free survival
genome wide
stem cells
gene expression
long non coding rna
dna methylation
genome wide identification
transcription factor
replacement therapy