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Effect of the Orally Active Growth Hormone Secretagogue MK-677 on Somatic Growth in Rats.

Junghun LeeAhreum KwonHyun Wook ChaeWoo Jung LeeTae Hyuk KimHo Seong Kim
Published in: Yonsei medical journal (2019)
Our results suggest that prolonged administration of MK-677 in rats does not promote growth despite the GH stimulatory effect of MK-677, which may be related to increased expression of SST in the hypothalamus. Further studies are needed to overcome the observed desensitization to GHS.
Keyphrases
  • growth hormone
  • poor prognosis
  • binding protein
  • long non coding rna