Gene-gene interaction between PPAR gamma 2 and ADR beta 3 increases obesity risk in children and adolescents.

M C OchoaA MartiC AzconaM ChuecaM OyarzábalR PelachA PatiñoM J Moreno-AliagaM A Martínez-GonzálezJ A Martíneznull null

Published in: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity (2005)

A synergistic effect between polymorphism Pro12Ala of the PPAR gamma 2 gene and Trp64Arg of the ADR beta 3 gene for obesity risk was found in a case-control study including children and adolescents.

Keyphrases

insulin resistance
copy number
genome wide
metabolic syndrome
genome wide identification
weight loss
adipose tissue
emergency department
adverse drug
skeletal muscle
fatty acid