Lung function in children with cystic fibrosis in the USA and UK: a comparative longitudinal analysis of national registry data.

Daniela K SchlüterJosh S OstrengaSiobhán B CarrAliza K FinkAlbert FaroRhonda D SzczesniakRuth H KeoghSusan C CharmanBruce C MarshallChristopher H GossDavid Taylor-Robinson

Published in: Thorax (2021)

Children with CF and homozygous F508del genotype in the USA had better lung function than UK children. These differences do not appear to be explained by early growth or nutrition, but differences in the use of early treatments need further investigation.

Keyphrases

lung function
cystic fibrosis
chronic obstructive pulmonary disease
air pollution
young adults
cross sectional
machine learning
big data
deep learning