The multiple effects of fecal microbiota transplantation on diarrhea-predominant irritable bowel syndrome (IBS-D) patients with anxiety and depression behaviors.
Hao LinQingqing GuoZhiyong WenSonglin TanJie ChenLijian LinPengcheng ChenJianquan HeJianbo WenYe ChenPublished in: Microbial cell factories (2021)
FMT treatment can effectively alleviate the anxiety and depression behaviors of IBS-D patients and reduce the IBS-SSS score, indicating that FMT can improve patients' symptoms. The high throughput sequencing results show that Bifidobacterium and Escherichia play the most critical role in the formation and recovery of IBS-D patients. The GC/MS data indicated that faeces isovaleric acid and valeric acid might be more suitable as a metabolic indicator of IBS-D remission. Trial registration ChiCTR, ChiCTR1900024924, Registered 3 August 2019, https://www.chictr.org.cn/showproj.aspx?proj=41676 .
Keyphrases
- irritable bowel syndrome
- end stage renal disease
- ejection fraction
- newly diagnosed
- prognostic factors
- randomized controlled trial
- peritoneal dialysis
- stem cells
- clinical trial
- patient reported outcomes
- systemic lupus erythematosus
- high throughput sequencing
- depressive symptoms
- disease activity
- artificial intelligence
- phase iii
- sleep quality