Evaluating the Contribution of Cell Type-Specific Alternative Splicing to Variation in Lipid Levels.
Katerina A B GawronskiWilliam P BoneYoSon ParkEvanthia E PashosBrandon M WenzMax F DudekXiao WangWenli YangDaniel James RaderKiran MusunuruBenjamin F VoightChristopher D BrownPublished in: Circulation. Genomic and precision medicine (2023)
These results provide an important foundation for future efforts that use iPSC and iPSC-derived cells to evaluate genetic mechanisms influencing both cardiovascular disease risk and complex traits in general.