Variable CD18 expression in a 22-year-old female with leukocyte adhesion deficiency I: Clinical case and literature review.
Anastasiia V BondarenkoOksana R BoyarchukInga S SakovichEkaterina A PolyakovaAlexander A MigasAleksandra N KupchinskayaAleksandra OpalinskaAdam ReichLiubov VolianskaAnna M HilfanovaFedir I LapiyLiudmyla I ChernyshovaAlla P VolokhaDariia V ZabaraMikhail V BelevtsevTatsiana V ShmanLyudmila V KukharenkoMikhail V GoltsevTatsiana G DubouskayaAndrei Y HancharouWeizhen JiSaquib LakhaniCarrie L LucasOlga V AleinikovaSvetlana O SharapovaPublished in: Clinical case reports (2023)
-lymphocytes were predominantly memory/effector cytotoxic T cells. However, revertant mosaicism was not being established suggesting that CD18 expression variability may be mediated by other mechanisms such as different β2 integrin isophorms expression.