Refinement of the CS6-expressing enterotoxigenic Escherichia coli strain B7A human challenge model: A randomized trial.
Kawsar R TalaatChad K PorterKayla M JaepChristopher A DuplessisRamiro L GutierrezMilton MacielBrittany AdjoodaniBrittany FeijooSubhra ChakrabortyJessica BrubakerStefanie A TropMark S RiddleSabrina S JosephA Louis BourgeoisMichael G ProutyPublished in: PloS one (2020)
An overnight fast enabled a reduction in the B7A inoculum dose; however, the attack rate was inconsistent and protection upon rechallenge was minimal.