Efficacy and safety of single injection of cross-linked sodium hyaluronate vs. three injections of high molecular weight sodium hyaluronate for osteoarthritis of the knee: a double-blind, randomized, multi-center, non-inferiority study.

Chul-Won HaYong-Beom ParkChong-Hyuk ChoiHee-Soo KyungJu-Hong LeeJae Doo YooJu-Hyung YooChoong-Hyeok ChoiChang-Wan KimHee-Chun KimKwang-Jun OhSeong-Il BinMyung Chul Lee

Published in: BMC musculoskeletal disorders (2017)

ClinicalTrials.gov ( NCT01510535 ). This trial was registered on January 6, 2012.

Keyphrases

phase iii
phase ii
knee osteoarthritis
ultrasound guided
open label
double blind
clinical trial
total knee arthroplasty
rheumatoid arthritis
study protocol
placebo controlled
randomized controlled trial