The Prognostic Role of CDK9 in Bladder Cancer.

Jędrzej Borowczak Krzysztof SzczerbowskiMateusz ManiewskiMarek ZdrenkaPiotr SłupskiPaulina AntosikSylwia KołodziejskaMarta Sekielska-DomanowskaMariusz DubielMagdalena BodnarŁukasz Szylberg

Published in: Cancers (2022)

High CDK9 expression predicts a favorable prognosis in urothelial carcinoma and is associated with clinicopathological features characteristic for early-stage disease. The decrease in CDK9 expression can be associated with the build-up of genetic instability and may indicate a key role for CDK9 in the early stages of urothelial carcinoma.

Keyphrases

cell cycle
early stage
poor prognosis
cell proliferation
genome wide
copy number
radiation therapy
sentinel lymph node
rectal cancer