Impaired Langerhans cell migration in psoriasis is due to an altered keratinocyte phenotype induced by interleukin-17.

L H EatonK T MellodySuzanne M PilkingtonR J DearmanI KimberC E M Griffiths

Published in: The British journal of dermatology (2018)

Collectively, these data suggest that an altered KC secretome, driven by increased expression of IL-17, is responsible for impaired LC migration in the uninvolved skin of patients with psoriasis.

Keyphrases

cell migration
poor prognosis
electronic health record
atopic dermatitis
big data
simultaneous determination
mass spectrometry
wound healing
long non coding rna
data analysis
deep learning