Incidence and Health Related Quality of Life of Opioid-Induced Constipation in Chronic Noncancer Pain Patients: A Prospective Multicentre Cohort Study.
Dalila R VeigaLiliane MendonçaRute SampaioJosé Manuel Castro-LopesLuís F AzevedoPublished in: Pain research and treatment (2018)
Constipation is a common adverse event among opioid users with major functional and quality of life impairment. These findings emphasise the need of OIC adequate assessment and management.
Keyphrases
- chronic pain
- pain management
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- irritable bowel syndrome
- risk factors
- clinical trial
- prognostic factors
- emergency department
- randomized controlled trial
- high glucose
- diabetic rats
- patient reported outcomes
- oxidative stress
- endothelial cells
- spinal cord
- double blind
- stress induced
- abdominal pain