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Paracoccidioidomycosis manifested by sarcoid-like cutaneous lesions with severe systemic disease: a rare and challenging diagnosis.

Bruna Dos Anjos BortoliniRachel Bertolani do Espírito SantoLucia Martins DinizRobson Dettmann JarskeNatália Tebas de Castro
Published in: Revista da Sociedade Brasileira de Medicina Tropical (2024)
Cutaneous involvement in paracoccidioidomycosis (PCM) can exhibit a highly polymorphic spectrum. The infiltrative pattern corresponds to up to 26.6% of observed skin lesions, including sarcoid-like plaques, a rare presentation of cutaneous lesions in PCM. This clinical expression is almost exclusively cutaneous, and its histology reveals a tuberculoid granuloma with a scarcity of fungi, leading to misdiagnosis as other granulomatous diseases. Here, we report a rare form of chronic multifocal paracoccidioidomycosis manifesting as sarcoid-like skin lesions misdiagnosed as granulomatous rosacea in a patient with severe systemic disease.
Keyphrases
  • case report
  • poor prognosis
  • interstitial lung disease
  • wound healing
  • rheumatoid arthritis
  • systemic sclerosis