Human Neutrophil Defensin-1, -3, and -4 Are Elevated in Nasal Aspirates from Children with Naturally Occurring Adenovirus Infection.
V S PriyadharshiniF Ramírez-JiménezM Molina-MacipC Renteria-RosalesJ Santiago-CruzPaola Zarate-SeguraE Lara-PadillaLuis Manuel TeránPublished in: Canadian respiratory journal (2018)
Our finding supports the involvement of HNP-1, -3, and -4 in naturally occurring cold in children infected with adenovirus. Because of their known antiviral properties, it is tempting to hypothesize that HNPs might play a protective role in adenovirus-induced respiratory disease; however, this remains to be shown.