SWnet: a deep learning model for drug response prediction from cancer genomic signatures and compound chemical structures.
Zhaorui ZuoPenglei WangXiaowei ChenLi TianHui GeDahong QianPublished in: BMC bioinformatics (2021)
We implemented an extended Graph Neural Network for molecular graphs and Convolutional Neural Network for gene features. With the employment of multi-tasking and self-attention functions to monitor the similarity between compounds, our model outperforms recently published methods using the same training and testing datasets.