RNA sequencing and Immunohistochemistry Reveal ZFN7 as a Stronger Marker of Survival than Molecular Subtypes in G-CIMP-negative Glioblastoma.
Anna Esteve-CodinaFrancesc AlamedaCristina CarratoEstela Pineda LosadaOriol ArpíMaria Martinez-GarcíaMar MalloMarta GutMarc DabadAvelina TortosaSonia Del BarcoJaume CapelladesJosep PuigOscar GallegoTeresa PujolLaura OleagaJuan Miguel Gil-GilCristian de Quintana-SchmidtIzaskun ValduviecoAnna Martinez-CardusBeatriz BellosilloAna Maria Muñoz-MarmolAnna EsteveMarta DomenechAngels CaminsJordi Craven-BartleSalvador VillaJordi MarruecosNuria de la IglesiaCarmen BalanaPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
TCGA and IGS molecular classifications of glioblastoma have no higher prognostic value than individual genes and should be refined before being applied to clinical trials.