Aging and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca2+ responses, and neuron cell death in cultured rat hippocampal neurons.

María Calvo-RodríguezCarmen de la FuenteMónica García-DurilloCarmen García-RodríguezCarlos VillalobosLucía Núñez

Published in: Journal of neuroinflammation (2017)

Aging and amyloid β oligomers, the neurotoxin involved in Alzheimer's disease, enhance TLR4 expression as well as LPS-induced Ca2+ responses and neuron cell death in rat hippocampal neurons aged in vitro.

Keyphrases

lps induced
inflammatory response
cell death
poor prognosis
toll like receptor
spinal cord
oxidative stress
cell cycle arrest
immune response
binding protein
cognitive decline
endothelial cells
nuclear factor
spinal cord injury
protein kinase
temporal lobe epilepsy
blood brain barrier