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Gestational Diabetes Mellitus, Postpartum Lipidomic Signatures, and Subsequent Risk of Type 2 Diabetes: A Lipidome-Wide Association Study.

Guoying WangJessie P BuckleyTami R BartellXiumei HongColleen PearsonXiaobin Wang
Published in: Diabetes care (2023)
GDM was associated with a wide range of lipid metabolic alterations at early postpartum, among which some lipid species were also associated with incident T2D and mediated the progression from GDM to T2D. The improvements attained by including lipid species in the prediction of T2D provides new insights regarding the early detection and prevention of progression to T2D.
Keyphrases
  • fatty acid
  • pregnant women
  • type diabetes
  • genome wide
  • genetic diversity
  • gene expression